Histology-informed spatial domain identification through multi-view graph convolutional networks
Huihui Zhang, Jiaxing Chang, Yue Sun, Pinli Hu, Jing Liu, Jiuju Luo, Hang Yang, Yonglin Ren, Xingtan Zhang, Zehua Chen, Kok Wai Wong, Haojing Shao
This paper introduces STESH, a spatial transcriptomics clustering method that integrates gene expression, spatial location, and histology, achieving superior clustering accuracy across multiple tissue types.
PLoS Computational Biology · Jun 1, 2026Peer-reviewedBioinformatics