Author

Hanna Moscho

University of Cambridge

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Synthetic Biology· 1

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:statistical model· 1

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Florian HollfelderiD· 1 shared Hannes Bormke· 1 shared Matthew PenneriD· 1 shared Michal Lihan· 1 shared Paul DupreeiD· 1 shared Peter Nix· 1 shared

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Florian HollfelderORCID

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Synthetic BiologybioRxivPreprintApr 23, 2026

Unsupervised protein language models learn patterns of enzyme function

Matthew Penner, Michal Lihan, Hannes Bormke…·Florian Hollfelder

This paper introduces a framework using protein language models to discover novel enzymes with specific functions by clustering sequence embeddings and recursively exploring functional reservoirs.

DOI 10.64898/2026.04.23.720319

protein sequencedeep learning

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