Cancer BiologybioRxivPreprint
Integration of Patient-Derived Organoids and Organ-on-Chip Systems: Investigating Colorectal Cancer Invasion within the Mechanical and GABAergic Tumor Microenvironment
Carly Strelez, Rachel G. Perez, John S. Chlystek…·Shannon M. Mumenthaler
This paper combines patient-derived organoids with a microfluidic organ-on-chip system to study colorectal cancer invasion under mechanical and GABAergic influences, showing enhanced invasiveness in KRAS mutant tumors.
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