Author

Hao Dong

Beijing Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Chenxuan JiiD· 1 shared Chuanyang Zhang· 1 shared Chunyu Cheng· 1 shared Fa ZhangiD· 1 shared Fuwei LiiD· 1 shared Jing Chen· 1 shared Jun Huo· 1 shared Min Zang· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBioinformatics

Chenxuan JiORCID

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3 papers

Recent·Most cited

CryoMV: Structure-Prior-Guided Modeling and Real-Particle Validation of Continuous Conformational Transitions in Cryo-EM

Fuwei Li, Hao Dong, Shuai Tang, Xinsheng Wang, Chuanyang Zhang, Chenxuan Ji, Renmin Han, Fa Zhang, Xiaohua Wan

CryoMV generates and validates continuous protein conformations from cryo-EM data using structure priors and real-particle validation, achieving high resolution and robustness on benchmark datasets.

bioRxiv · Sep 27, 2026 · PreprintBioinformatics

A high-throughput immunopeptidome platform for MHC II alleles to characterize antigen-specific CD4 + T cells

Jing Chen, Xu Zhu, Jun Huo, Shang Wu, Ting Zhou, Chunyu Cheng, Hao Dong, Yan Li, Xianchi Dong, Yuxin Chen

The paper develops EliteMHCII, a high-throughput platform to identify MHC II epitopes and assess peptide binding affinity, showing high-affinity peptides correlate with strong CD4+ T cell responses.

bioRxiv · Jun 5, 2025Biochemistry

Computational Analysis of Zn2+ Mediated Non-Competitive Inhibition to Caspase-3

Xinyu Erya Tian, Min Zang, Xiaoyu Wang, Hao Dong

This study uses computational methods to analyze Zn2+-mediated non-competitive inhibition of caspase-3, revealing atomic-level insights into its mechanism and potential therapeutic applications.

bioRxiv · Sep 30, 2024 · PreprintBiophysics