Author

Harikrishna Thulaseedharan

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Andrew T. Watt· 1 shared Ashley Dung· 1 shared Christopher J. Torio· 1 shared Dan DominissiniiD· 1 shared Isaac TangiD· 1 shared Joseph G. GleesoniD· 1 shared Julie DouvilleiD· 1 shared Konstantina Skourti-StathakiiD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperGenetic & Genomic Medicine

Andrew T. Watt

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1 paper

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJul 22, 2026

ASXL3 truncating patient variants mediate transcriptional gain-of-function and are antisense oligonucleotide-responsive

Yuji Nakamura, Toan Nguyen, Nofar Mor…·Joseph G. Gleeson

The paper shows ASXL3 truncating variants cause disease via gain-of-function, not loss-of-function, and demonstrates antisense oligonucleotides can reverse the transcriptional effects.

1 citation

humanbulk RNA-seq

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