Molecular BiologySLAS DISCOVERYPeer-reviewed
Quantitative target engagement of RIPK1 in human whole blood via the cellular thermal shift assay for potential pre-clinical and clinical applications
Shitalben Patel, Marie Karlsson, Joseph T. Klahn…·James E. Kath
This paper develops quantitative CETSA(R) methods in unprocessed human whole blood for measuring target engagement of RIPK1 inhibitors, showing high sensitivity and robustness.
1 citation