Huan Wang

Development of a genetically encoded fluorescent indicator for monitoring GPR52 activation

The paper develops a genetically encoded fluorescent sensor to monitor GPR52 activation, enabling detection of endogenous ligand release and real-time activation monitoring.

Selective GRAB sensors reveal distinct endocannabinoid dynamics in vivo

The paper develops selective fluorescent sensors to detect endocannabinoid dynamics in vivo and shows that Δ9-THC induces sustained 2-AG signaling in the nucleus accumbens.

Simultaneous, real-time tracking of many neuromodulatory signals with Multiplexed Optical Recording of Sensors on a micro-Endoscope

This paper develops a micro-endoscope probe to simultaneously track multiple neuromodulators in real time using fluorescent sensors, demonstrating its use in brain slices and awake mice.

A genetically encoded fluorescent sensor for monitoring spatiotemporal prostaglandin E2 dynamics in vivo

This paper develops a genetically encoded fluorescent sensor, GRABPGE2-1.0, to monitor spatiotemporal PGE2 dynamics in vivo with high resolution.

Pandemic preparedness through genomic surveillance: Overview of mutations in SARS-CoV-2 over the course of COVID-19 outbreak

The paper analyzes SARS-CoV-2 mutations across 8 million sequences to identify high-mutability proteins and predict surges, providing real-time genomic surveillance.

Future COVID-19 surges prediction based on SARS-CoV-2 mutations surveillance

The paper predicts future COVID-19 surges by analyzing SARS-CoV-2 mutations in real time using genomic surveillance data.

BOLD fMRI signals of visual white matter encode visuotopic information and predict effective connectivity between visual areas

Infectious bronchitis virus attaches to lipid rafts and enters cells via clathrin mediated endocytosis

This study identifies the molecular mechanisms of infectious bronchitis virus (IBV) entry, showing it attaches to lipid rafts and enters via clathrin-mediated endocytosis, followed by endosomal trafficking and membrane fusion.

Human pancreatic β cell lncRNAs control cell-specific regulatory networks

This study identifies β cell-specific lncRNAs that regulate transcriptional networks and show dysregulation in type 2 diabetes.

Bayesian Inference of Two-Dimensional Contrast Sensitivity Functions

This study introduces a Bayesian framework for estimating contrast sensitivity functions, showing improved accuracy and precision compared to traditional methods with similar observation requirements.