Cancer BiologyNucleic Acids ResearchPeer-reviewed
An RNA editing/binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer
Lihua Qi, Yangyang Song, Tim Hon Man Chan…·Leilei (Polly) Chen
This study reveals a non-editing gene regulatory role of ADARs in cancer by enhancing miR-27a processing, which represses METTL7A expression, highlighting a new therapeutic target.
DOI 10.1093/nar/gkx667