Genetic & Genomic MedicineMolecular Biology and EvolutionPeer-reviewed
A phylogeny-aware GWAS framework to correct for heritable pathogen effects on infectious disease traits
Sarah Nadeau, Christian Wandall Thorball, Roger D. Kouyos…·S Yerly
This paper introduces a phylogeny-aware GWAS framework to correct for heritable pathogen effects on infectious disease traits, showing improved detection of host genetic variants in simulations and applied to HIV-1 data.
DOI 10.1093/molbev/msac163