Author

I. Chambers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

N. Mullin· 3 shared D. Colby· 2 shared E. Hall-Ponsele· 2 shared R. Pantier· 2 shared A. Corsinotti· 1 shared D. Kelly· 1 shared E. S. Mirfazeli· 1 shared F. C. Wong· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBiochemistry

N. Mullin

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Author profile →

3 papers

Recent·Most cited

TET1 interacts directly with NANOG via independent regions containing hydrophobic and aromatic residues

R. Pantier, N. Mullin, E. Hall-Ponsele, I. Chambers

This study identifies the regions of TET1 that interact with NANOG, showing that these interactions are mediated by conserved hydrophobic and aromatic residues and occur at pluripotency enhancers.

bioRxiv · Jun 29, 2020Biochemistry

Analysis of pluripotency transcription factor interactions reveals preferential binding of NANOG to SOX2 rather than NANOG or OCT4

T. K. Mistri, D. Kelly, J. Mak, D. Colby, N. Mullin, I. Chambers

This study investigates the interactions of pluripotency transcription factors Nanog, Sox2, and Oct4, revealing Nanog's preferential binding to Sox2 over Oct4 and its ability to form homomultimers.

bioRxiv · Jun 24, 2020 · PreprintBiochemistry

Distinct SoxB1 networks are required for naïve and primed pluripotency

A. Corsinotti, F. C. Wong, T. Tatar, I. Szczerbinska, F. Halbritter, D. Colby, S. Gogolok, R. Pantier, K. Liggat, E. S. Mirfazeli, E. Hall-Ponsele, N. Mullin, V. Wilson, I. Chambers

The paper shows that distinct SoxB1 networks support naïve and primed pluripotency, with different expression balances of Sox2 and Sox3 in ESCs and EpiSCs.

bioRxiv · Dec 6, 2017Cell Biology