Monitoring Unfolding of Titin I27 single- and bi-Domain with High-Pressure NMR Spectroscopy.
C. ROUMESTAND, I. HERRADA, M. VAN HEUSDEN, P. BARTHE, K. DEGUILLEN, L. MAMMRI, S. DELBECQ, F. Rico
This study uses high-pressure NMR to analyze the unfolding of titin I27 domains, confirming the AG β-sheet as a critical structural element and revealing differences from previous MD simulation findings.
bioRxiv · Mar 31, 2018Biophysics