Author

I. Kline

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

J. G. Purdy· 2 shared Y. Xi· 2 shared C. C. Weihl· 1 shared C. S. Clemen· 1 shared J. Paulo· 1 shared J. von Einem· 1 shared J. Zhu· 1 shared L. Lindenmayer· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

J. G. Purdy

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2 papers

Recent·Most cited

The p97-UBXD8 complex modulates ER-Mitochondria contact sites by modulating membrane lipid saturation and composition

R. Ganji, J. Paulo, Y. Xi, I. Kline, J. Zhu, C. S. Clemen, C. C. Weihl, J. G. Purdy, S. Gygi, M. Raman

This study shows that the p97-UBXD8 complex regulates ER-mitochondria contact sites by modulating membrane lipid saturation and composition, with implications for neurodegenerative diseases.

bioRxiv · Dec 8, 2021 · PreprintCell Biology

Human Cytomegalovirus uses a Host Stress Response to Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very Long Chain Fatty Acids

Y. Xi, L. Lindenmayer, I. Kline, J. von Einem, J. G. Purdy

This study shows that PERK, part of the ER stress pathway, differentially regulates fatty acid elongation enzymes to balance lipid synthesis in HCMV-infected cells, supporting viral replication.

mBio · Jun 29, 2021Peer-reviewedMicrobiology