Author

I. Kucinski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:trajectory inference· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

B. Göttgens· 2 shared M. Barile· 2 shared A. C. Wilkinson· 1 shared A. Clay· 1 shared A. H. Cull· 1 shared B. Gottgens· 1 shared D. Bode· 1 shared D. G. Kent· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

B. Göttgens

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3 papers

Recent·Most cited

A time and single-cell resolved model of hematopoiesis

I. Kucinski, J. Campos, M. Barile, F. Severi, N. Bohin, P. N. Moreira, L. Allen, H. Lawson, M. L. R. Haltalli, S. J. Kinston, D. O'Carroll, K. R. Kranc, B. Göttgens

The paper builds a real-time, quantitative model of hematopoiesis using time-series single-cell RNA-Seq and persistent labeling, revealing lineage-specific self-renewal and differentiation properties.

bioRxiv · Sep 7, 2022 · PreprintCell Biology

A highly efficient reporter system for identifying and characterizing in vitro expanded hematopoietic stem cells

J. L. C. Che, D. Bode, I. Kucinski, A. H. Cull, F. Bain, M. Barile, G. Boyd, M. Belmonte, M. Jassinskaja, J. Rubio-Lara, M. S. Shepherd, A. Clay, A. C. Wilkinson, H. Nakauchi, S. Yamazaki, , D. G. Kent

This paper introduces a reporter system to identify and characterize expanded hematopoietic stem cells, showing their molecular profile resembles fetal liver HSCs and shares gene expression signatures with functional HSCs from various sources.

bioRxiv · Jun 18, 2021 · PreprintCell Biology

Single-cell molecular profiling provides a high-resolution map of basophil and mast cell differentiation

F. K. Hamey, W. W. Y. Lau, I. Kucinski, X. Wang, E. Diamanti, N. K. Wilson, B. Gottgens, J. S. Dahlin

This study maps basophil and mast cell differentiation using single-cell RNA sequencing and flow cytometry in mice, revealing distinct trajectories and lineage-specific gene regulation.

bioRxiv · Nov 21, 2019Immunology