Author

I. Nazy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:proteomics· 3 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. G. Ivanov· 3 shared I. A. Kaltashov· 3 shared N. Ivetic· 2 shared S. N. Nguyen· 2 shared Y. Du· 2 shared D. Favre· 1 shared H. S. Le· 1 shared J. W. Smith· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

D. G. Ivanov

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Reverse engineering of a pathogenic antibody reveals the molecular mechanism of vaccine-induced immune thrombotic thrombocytopenia

D. G. Ivanov, N. Ivetic, Y. Du, S. N. Nguyen, H. S. Le, D. Favre, I. Nazy, I. A. Kaltashov

This paper identifies a pathogenic antibody causing VITT, characterizes its structure and function, and reveals the molecular mechanism involving electrostatic interactions and immune complex formation.

bioRxiv · Jun 30, 2023Immunology

Structural characterization of a pathogenic antibody underlying vaccine-induced immune thrombotic thrombocytopenia (VITT)

S. N. Nguyen, S.-H. Le, D. G. Ivanov, N. Ivetic, I. Nazy, I. A. Kaltashov

This paper characterizes a pathogenic anti-PF4 antibody from VITT patients, revealing its monoclonal nature, N-glycosylation site, and subclass composition.

bioRxiv · May 28, 2023Biochemistry

Molecular architecture and platelet-activating properties of small immune complexes assembled on intact heparin and their possible involvement in heparin-induced thrombocytopenia

Y. Yang, Y. Du, D. G. Ivanov, R. Clare, J. W. Smith, I. Nazy, I. A. Kaltashov

This study characterizes small immune complexes formed by PF4, heparin, and HIT antibodies using native mass spectrometry, revealing their structure and platelet-activating properties.

bioRxiv · Feb 11, 2023 · PreprintBiochemistry