Human vulnerability to cancer malignancy is enhanced by evolution of higher mesenchymal CD44 expression compared to other mammals
X. Ma, A. Dighe, J. Maziarz, E. Neumann, E. Erkenbrack, Y.-Y. Hei, Y. Liu, Y. Suhail, K. Kshitiz, I. Pak, A. Levchenko, G. Wagner
This study shows that increased CD44 expression in human skin and endometrial stromal fibroblasts, compared to other mammals, correlates with higher cancer vulnerability.
bioRxiv · Aug 3, 2020 · PreprintEvolutionary Biology