Author

A. Dighe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:comparative / phylogenetic analysis· 2 Organism:multiple species· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Levchenko· 2 shared G. Wagner· 2 shared J. Maziarz· 2 shared Kshitiz· 2 shared Y. Suhail· 2 shared A. IbrahimHashim· 1 shared E. Erkenbrack· 1 shared E. Neumann· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersEvolutionary Biology

A. Levchenko

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Author profile →

3 papers

Recent·Most cited

Experimental and Phylogenetic Evidence for Correlated Gene Expression Evolution between Dermal and Endometrial Fibroblasts: implications for the evolution of cancer malignancy

A. Dighe, J. Maziarz, A. IbrahimHashim, R. Gatenby, Kshitiz, A. Levchenko, G. P. Wagner

The paper investigates correlated gene expression evolution between dermal and endometrial fibroblasts across species and in an experimental model, finding significant correlations that support evolutionary links to cancer malignancy.

bioRxiv · Jul 8, 2023 · PreprintEvolutionary Biology

Cis-Regulatory Differences Explaining Evolved Levels of Endometrial Invasibility in Eutherian Mammals

Y. Suhail, J. D. Maziarz, A. Dighe, G. Wagner, Kshitiz

The paper identifies cis-regulatory differences in genomic sequences that explain species-specific variations in endometrial invasibility and their link to gene expression and stromal properties.

bioRxiv · Sep 4, 2020 · PreprintEvolutionary Biology

Human vulnerability to cancer malignancy is enhanced by evolution of higher mesenchymal CD44 expression compared to other mammals

X. Ma, A. Dighe, J. Maziarz, E. Neumann, E. Erkenbrack, Y.-Y. Hei, Y. Liu, Y. Suhail, K. Kshitiz, I. Pak, A. Levchenko, G. Wagner

This study shows that increased CD44 expression in human skin and endometrial stromal fibroblasts, compared to other mammals, correlates with higher cancer vulnerability.

bioRxiv · Aug 3, 2020 · PreprintEvolutionary Biology