I. Perez

Single NV in nanodiamond for quantum sensing of protein dynamics in an ABEL trap

The paper uses a single NV center in a nanodiamond within an ABEL trap to quantum-sense protein dynamics, specifically tracking ATP-driven conformational changes in FoF1-ATP synthase with high spatio-temporal resolution.

Mechanism of ADP-inhibited ATP hydrolysis in single proton-pumping FoF1-ATP synthase trapped in solution

The paper investigates how ADP inhibits ATP hydrolysis in single Escherichia coli FoF1-ATP synthases, revealing that ADP reduces active enzymes rather than uniformly slowing catalytic turnover.

Monitoring oligomerization dynamics of individual human neurotensin receptors 1 in living cells and in SMALP nanodiscs

This study uses SMALP nanodiscs to monitor oligomerization dynamics of NTSR1 in living cells before and after ligand stimulation.

Mutational screens highlight glycosylation as a modulator of CSF3R activity

The paper identifies glycosylation sites as critical for CSF3R activity and shows that mutations at these sites can lead to ligand-independent cell growth in chronic neutrophilic leukemia.

The CRY1 tail controls circadian timing by regulating its association with CLOCK:BMAL1

The study identifies the CRY1 tail's role in regulating its interaction with CLOCK:BMAL1, affecting circadian timing and linking it to Delayed Sleep Phase Disorder.