Author

I. Puoti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. B. Frost· 1 shared A. Ciulli· 1 shared A. Kombara· 1 shared A. Stingu· 1 shared B. De Servi· 1 shared C. Kofink· 1 shared C. Whitworth· 1 shared E. Diers· 1 shared

Activity by Year

2014-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. B. Frost

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2 papers

Recent·Most cited

Confounding factors in targeted degradation of short-lived proteins

V. Vetma, L. C. Perez, J. Elias, A. Stingu, A. Kombara, T. Gmaschitz, N. Braun, T. Ciftci, G. Dahmann, E. Diers, T. Gerstberger, P. Greb, G. Kidd, C. Kofink, I. Puoti, , M. Koegl

This study shows that the natural half-life of a target protein significantly affects degradation by degrader agents and highlights confounding factors in screening for protein degraders.

bioRxiv · Feb 19, 2024Cancer Biology

Evidences of a cytotoxic activity of S-adenosylmethionine on OCI-AML3 cells

K. Aprile von Hohenstaufen, I. Puoti, M. Meloni, B. De Servi

This paper investigates the cytotoxic effect of S-adenosylmethionine (SAM) on OCI-AML3 cells and finds it induces cell death without significant apoptosis at concentrations achievable in humans.

bioRxiv · May 8, 2014 · PreprintPharmacology & Toxicology