I. Rothenaigner

This study develops a high-throughput method to generate reliable human brain organoids for modeling microcephaly, glioma invasion, and drug screening.

This study shows that suppressing ferroptosis via antioxidants or vitamin A is necessary for proper neuronal development and laminar organization in cortical organoids.

CellDeathPred uses deep learning on cell painting images to predict ferroptosis and apoptosis with 95% accuracy in human cells.

This study identifies FXR agonists that suppress ferroptosis by upregulating protective proteins, highlighting FXR's role in preventing lipid peroxidation and ferroptotic cell death.

This study identifies acriflavine as a potent inhibitor of SARS-CoV-2 and other betacoronaviruses, effective in cellular models, in vivo, and ex vivo.