Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
P. Grygier, K. Pustelny, F. Menezes…·A. Czarna
The paper determines the crystal structures of DYRK1B and DYRK1A in complex with AZ191, identifying structural differences that inform selective inhibitor design.
A. Czarna, J. Plewka, L. Kresik…·K. Pyrc
The paper presents the crystal structure of SARS-CoV-2 nsp14 in apo-form and explains how nsp10 modulates its exonuclease activity through structural changes.
A. Matsuda, J. Plewka, Y. Chykunova…·A. Czarna
This study demonstrates that SARS-CoV-2 proteins nsp14, nsp10, and nsp16 form a heterotrimer complex, which modulates nsp14's exonuclease activity and protects viral RNA.
V. Napolitano, A. Dabrowska, K. Schorpp…·K. Pyrc
This study identifies acriflavine as a potent inhibitor of SARS-CoV-2 and other betacoronaviruses, effective in cellular models, in vivo, and ex vivo.