High-resolution scRNA-seq reveals genomic determinants of antigen expression hierarchy in African Trypanosomes
K. R. McWilliam, Z. Keneskhanova, R. O. Cosentino, A. Dobrynin, J. E. Smith, I. Subota, M. R. Mugnier, M. Colome-Tatche, T. N. Siegel
This study uses high-resolution scRNA-seq to uncover how genomic rearrangements during antigen switching in Trypanosoma brucei depend on repair mechanisms and homologous templates.
bioRxiv · Mar 22, 2024 · PreprintMicrobiology