S. Schuster

Learning and cognition in highspeed decision making

This study shows that highspeed decision making in archerfish is flexible and abstract, as they can reprogram their decisions to new rules and generalize to novel settings.

Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells

This study develops a method to generate optimized peptide ligands for CAR-T cell restimulation, demonstrating enhanced expansion and memory development in preclinical models.

The histone modifier KAT2A presents a selective target in a subset of well-differentiated microsatellite-stable colorectal cancers

This study identifies KAT2A as a therapeutic target in a subset of well-differentiated, microsatellite-stable colorectal cancers by showing its dependency and functional consequences.

CWLP and PRP940 form plasma-membrane nanodomain complexes with aquaporins, interact with PP2A and contribute to dehydration tolerance

This paper identifies CWLP and PRP940 as plasma-membrane nanodomain proteins that interact with aquaporins and PP2A, enhancing dehydration tolerance in plants.

Connexins evolved after early chordates lost innexin diversity

The paper investigates glycosylation patterns and diversity loss of innexins in chordates and non-chordates, finding that glycosylation is widespread and that early chordates lost innexin diversity, possibly leading to the dominance of connexins.

Unexpected plasticity in the life cycle of Trypanosoma brucei

This study shows that proliferating slender stage Trypanosoma brucei can infect tsetse flies as effectively as stumpy stages, challenging the traditional view of the parasite's life cycle.

Mapping the evolutionary landscape of Zika virus infection in immunocompromised mice.

This study establishes a ZIKV transmission model in immunocompromised mice to investigate factors influencing viral evolution and DVG production.

Calculating the optimal hematocrit under the constraint of constant cardiac power

This paper calculates the optimal hematocrit under constant cardiac power, finding values between 0.5 and 0.7, which explains improved exertional performance at higher hematocrit.