Cancer BiologybioRxivPreprint
ALK signaling drives tumorigenicity and chemoresistance of pancreatic ductal adenocarcinoma cells
B. Parejo-Alonso, A. Royo-Garcia, P. Espiau-Romera…·P. Sancho
This study shows that ALK signaling promotes tumorigenicity and chemoresistance in pancreatic cancer stem cells, and that ALK inhibitors can reduce CSC content and enhance chemotherapy effectiveness.
DOI 10.1101/2022.08.29.505637