Author

Ian Watson

Google (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:protein structure· 1

Frequent Co-Authors

Jianwen A. FengiD· 2 shared Wen TorngiD· 2 shared A. M. EdwardsiD· 1 shared Aiping DongiD· 1 shared Albina Bolotokova· 1 shared Aliakbar Khalili Yazdi· 1 shared Almagul Seitova· 1 shared Anthony D. KeefeiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Jianwen A. FengORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Medicinal ChemistryPeer-reviewedNov 4, 2024

A resource to enable chemical biology and drug discovery of WDR Proteins

Suzanne Z. Ackloo, Fengling Li, Magda Szewczyk…·C. H. Arrowsmith

The paper develops a resource for discovering ligands for WDR proteins using experimental and computational methods, leading to the identification of drug-like ligands for 9 out of 20 targets.

28 citations

humanprotein structure

𝕏 PostBluesky

BioinformaticsACS OmegaPeer-reviewedJul 6, 2023

A deep learning approach for the discovery of tumor-targeting small organic ligands from DNA-Encoded Chemical Libraries

Wen Torng, Ilaria Biancofiore, Sebastian Oehler…·Jianwen A. Feng

The paper uses deep learning to identify tumor-targeting ligands from DNA-encoded chemical libraries against CAIX, finding 70% of novel hits show submicromolar activity.

23 citations

deep learningdrug response / drug discovery

𝕏 PostBluesky