BiochemistryNature Structural & Molecular BiologyPeer-reviewed
Interfacial water confers transcription factors with dinucleotide specificity
Ekaterina Yu. Morgunova, Gábor Nagy, Yimeng Yin…·Jussi Taipale
The paper investigates how transcription factors recognize DNA dinucleotides through structural analysis, revealing water-mediated mechanisms that enhance specificity beyond mononucleotide recognition.