BiochemistrybioRxiv
M. tuberculosis meets European Lead Factory - identification and structural characterization of novel Rv0183 inhibitors using X-ray crystallography
Lina Riegler-Berket, Laura Gödl, Nakia Polidori…·Monika Oberer
This study identifies and characterizes novel Rv0183 inhibitors using high-throughput screening and X-ray crystallography, demonstrating species-selective inhibition against Mycobacterium tuberculosis.
DOI 10.1016/j.dist.2025.100002