Jürgen A. Bohnert

This study investigates in-host evolution of Klebsiella pneumoniae sequence type 147 isolates, revealing microevolution from classic to convergent pathotype through plasmid acquisition and capsular changes affecting virulence and morphology.

This study shows that temperatures above 37°C increase hypermucoviscosity and virulence in a convergent Klebsiella pneumoniae strain, potentially due to plasmid-encoded factors and temperature-dependent regulatory changes.

The paper describes a Klebsiella pneumoniae strain exhibiting phenotypic hyper-splitting, forming small colony variants and multiple morpho-resistotypes with clinical implications.

This study identifies unique pathogenic markers in Klebsiella pneumoniae through multi-omics analysis, suggesting potential novel antimicrobial targets.