Fibril elongation by human islet amyloid polypeptide is the main event linking aggregation to membrane damage
B. O. W. Elenbaas, S. M. Kremsreiter, L. Khemtemourian, J. A. Killian, T. Sinnige
This study investigates how hIAPP aggregation relates to membrane damage, finding that fibril elongation, not oligomers, is the main cause of vesicle leakage.
bioRxiv · Oct 14, 2022Biochemistry