J. Schimpf

Cochaperones convey the energy of ATP hydrolysis for directional action of Hsp90

This study shows how three cochaperones couple ATP hydrolysis to directional conformational changes in Hsp90 during kinase maturation.

Morphological and genetic diversity of maize landraces along an altitudinal gradient in the Southern Andes

The paper evaluates morphological and molecular diversity of maize landraces in the Southern Andes, revealing two coexisting gene pools along an altitudinal gradient.

Inferring kinetic rate constants from single-molecule FRET trajectories - a blind benchmark of kinetic analysis tools

This study benchmarks eleven tools for inferring kinetic rate constants from smFRET trajectories using simulated and experimental data with varying challenges.

Autophosphorylation of the KaiC-like protein ArlH inhibits oligomerisation and interaction with ArlI, the motor ATPase of the archaellum

This study shows that autophosphorylation of ArlH inhibits its oligomerization and interaction with ArlI, essential for archaellum function and motility.

Isolated Nuclei Stiffen in Response to Low Intensity Vibration

This study shows that isolated nuclei from mesenchymal stem cells become stiffer after low intensity vibration, involving the LINC complex but not LaminA/C or Sun-2.

Mass Photometry of Membrane Proteins

This study uses mass photometry to analyze membrane proteins and mimetic systems, revealing structural insights and improving nanodisc assembly characterization.

Quantifying the heterogeneity of macromolecular machines by mass photometry

This paper demonstrates that mass photometry accurately quantifies sample heterogeneity with high resolution and minimal volume, outperforming negative stain electron microscopy in detecting proteasome assemblies.