MicrobiologybioRxivPreprint
Host cell cAMP-Epac pathway inhibition by hawthorn extract as a potential treatment for Chagas disease
G. Ferri, L. R. Fernandez, G. T. Di Mario…·M. M. Edreira
This paper investigates hawthorn extract's effect on the host cell cAMP-Epac pathway, showing it inhibits Trypanosoma cruzi invasion and synergizes with nifurtimox to reduce treatment toxicity and cost.
DOI 10.1101/2023.01.26.525677