Author

J. A. Schalken

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Deshpande· 1 shared B. Wasylyk· 1 shared C. Wasylyk· 1 shared G. W. Verhaegh· 1 shared J. Brants· 1 shared O. van Hooij· 1 shared P. Mass· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Deshpande

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintDec 28, 2023

Novel inhibitors of TTLL12s oncogenic potential that overcome suppression of ligation of nitrotyrosine to the C-terminus of detyrosinated a-tubulin

A. Deshpande, J. Brants, C. Wasylyk…·B. Wasylyk

The paper identifies two molecules that activate nitrotyrosine ligation to detyrosinated α-tubulin by targeting TTLL12, which suppresses this process, suggesting potential therapeutic applications for cancer and related pathologies.

DOI 10.1101/2023.12.28.573570

proteomicsexperimental assay

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