Author

J. Aitken

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. H. Wei· 1 shared A. K. Enjeti· 1 shared A. M. Douglas· 1 shared A. Mannan· 1 shared B. Nixon· 1 shared C. de Bock· 1 shared D. A. Skerrett-Byrne· 1 shared D. Staudt· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. H. Wei

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMar 9, 2022

Blockade of redox second messengers inhibits JAK/STAT and MEK/ERK signaling sensitizing FLT3-mutant acute myeloid leukemia to targeted therapies

Z. P. Germon, J. R. Sillar, A. Mannan…·M. D. Dun

This study identifies the Rac-NOX2 complex as a driver of redox signaling in FLT3-mutant AML, showing that inhibiting NOX2 reduces key signaling pathways and enhances response to FLT3 inhibitors.

DOI 10.1101/2022.03.09.483687

humanproteomics

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