Ensemble Switching Unveils a Kinetic Rheostat Mechanism of the Eukaryotic Thiamine PyrophosphateRiboswitch
J. Ma, N. Saikia, S. Godar, G. L. Hamilton, F. Ding, J. Alper, H. Sanabria
This study reveals a kinetic rheostat mechanism in the Arabidopsis thiamine pyrophosphate riboswitch through ensemble switching dynamics involving TPP and Mg2+ interactions.
bioRxiv · Mar 12, 2021Biophysics