F. Ding

Displacement and dissociation of oligonucleotidesduring DNA hairpin closure under strain

This study measures oligonucleotide displacement during DNA hairpin closure under strain and develops a mathematical model to predict residence times under various conditions.

Cost-efficient boundary-free surface patterning achieves high effective-throughput of time-lapse microscopy experiments

This study introduces a boundary-free surface patterning method that enhances the effective-throughput of time-lapse microscopy by preventing cell loss during long-term recordings.

Fuzzy Supertertiary Interactions within PSD-95 Enable Ligand Binding

This study uses molecular dynamics and FRET to analyze PSD-95's conformational dynamics and shows how its flexible structure enables ligand binding.

SAMase of bacteriophage T3 inactivates E. coli methionine S-adenosyltransferase by forming hetero-polymers

This paper shows that bacteriophage T3's SAMase degrades SAM and inhibits E. coli's MAT by forming hetero-polymers, leading to metabolic disruption.

Ensemble Switching Unveils a Kinetic Rheostat Mechanism of the Eukaryotic Thiamine PyrophosphateRiboswitch

This study reveals a kinetic rheostat mechanism in the Arabidopsis thiamine pyrophosphate riboswitch through ensemble switching dynamics involving TPP and Mg2+ interactions.

Human H-ferritin presenting RBM of spike glycoprotein as potential vaccine of SARS-CoV-2

This paper describes the design of a fusion protein using human ferritin to present the SARS-CoV-2 spike glycoprotein RBM, suggesting it as a potential vaccine candidate.

Quantitative single-cell splicing analysis reveals an ‘economy of scale’ filter for gene expression

The paper introduces a method to measure splicing efficiency at single-cell level and finds it increases with gene expression levels, suggesting an economy of scale effect.