Cancer BiologybioRxivPreprint
Integrated Single-Cell Genotyping and Chromatin Accessibility Charts JAK2V617F Human Hematopoietic Differentiation
R. M. Myers, F. Izzo, S. Kottapalli…·D. A. Landau
This paper develops GoT-ChA to link genotypes to chromatin accessibility in single cells, revealing JAK2V617F mutation-induced epigenetic changes in hematopoietic differentiation.