Loss of circulating CD8α+ NK cells during human Mycobacterium tuberculosis infection
N. Mehanna, A. Pradhan, R. Kaur, T. Kontopoulos, B. Rosati, D. Carlson, N.-K. Cheung, H. Xu, J. Bean, K. Hsu, J.-B. Le Luduec, C. K. Vorkas
The paper identifies CD8+ NK cells as a Mtb-responsive population with enhanced maturity and cytotoxicity in human TB infection, correlating with disease resistance.
bioRxiv · Apr 16, 2024 · PreprintImmunology