Author

J. Bezney

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

G. A. Breuer· 1 shared G. P. Gupta· 1 shared N. R. Fons· 1 shared R. K. Sundaram· 1 shared R. S. Bindra· 1 shared W. Feng· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

G. A. Breuer

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1 paper

Recent·Most cited

CRISPR screening identifies novel PARP inhibitor classification based on distinct base excision repair pathway dependencies

G. A. Breuer, J. Bezney, N. R. Fons, R. K. Sundaram, W. Feng, G. P. Gupta, R. S. Bindra

This study identifies novel PARP inhibitor classifications based on distinct base excision repair pathway dependencies revealed through CRISPR screening, showing that PARP trapping and catalytic inhibition are not the only factors affecting their biological activity.

bioRxiv · Oct 18, 2020 · PreprintCancer Biology