Salt-inducible kinase (SIK) inhibition is protective in a mouse model of asthma
M. van Gijsel-Bonnello, N. J. Darling, L. McDonald, M. Sime, J. Clark, M. Mezna, A. Schuettelkopf, C. Mackay, J. Bower, H. McKinnon, P. Cohen, S. Arthur
This study shows that inhibiting SIKs reduces IL-13 secretion from ILC2s and alleviates allergic asthma symptoms in mice.
bioRxiv · Jun 7, 2021 · PreprintImmunology