J. Damborsky

This paper introduces CoVAMPnet, a framework to analyze how drug candidates affect disordered biomolecules, finding that TMP and SPA preserve structured conformations of Aβ42.

The paper investigates the catalytic mechanism and allosteric behavior of NanoLuc luciferase, revealing how ligand binding at different sites influences luminescence.

This study elucidates the catalytic mechanism of Renilla-type bioluminescence using crystallographic, spectroscopic, and computational methods, revealing key structural and electronic features involved in light emission.

The study finds a higher prevalence of Treponema spp. and double-species infections in Alzheimer's patients compared to controls using PCR and statistical analysis.

This paper describes the engineering of a hyperstable FGF2 variant with nine mutations using a computer-assisted strategy, achieving high stability without losing biological function.