Cytosolic factors controlling PASTA kinase-dependent ReoM phosphorylation
P. Rothe, S. Wamp, L. Rosemeyer, J. Rismondo, J. Doellinger, A. Grundling, S. Halbedel
This study identifies GpsB as an activator of PrkA, a PASTA kinase, and shows that ReoM phosphorylation is regulated by growth phase and phosphatase PrpC, with MurA's conformation and interaction with ReoM playing a key role.
bioRxiv · Apr 2, 2024Microbiology