A. Grundling

Cytosolic factors controlling PASTA kinase-dependent ReoM phosphorylation

This study identifies GpsB as an activator of PrkA, a PASTA kinase, and shows that ReoM phosphorylation is regulated by growth phase and phosphatase PrpC, with MurA's conformation and interaction with ReoM playing a key role.

Histidine and its uptake are essential for the growth of Staphylococcus aureus at low pH

This study identifies genes essential for Staphylococcus aureus growth at low pH, highlighting histidine transport's role in maintaining intracellular pH.

Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM

This paper investigates how GlmM inhibits the c-di-AMP cyclase CdaA in B. subtilis by forming a stable complex and blocking cyclase oligomerization.

Bacillus subtilis YngB contributes to wall teichoic acid glucosylation and glycolipid formation during anaerobic growth

This study identifies YngB as a UGPase in B. subtilis that contributes to WTA glucosylation and glycolipid formation under anaerobic conditions.

Phosphoglycerol-type wall- and lipoteichoic acids are enantiomeric polymers differentially cleaved by the stereospecific glycerophosphodiesterase GlpQ

This study demonstrates that WTA and LTA are enantiomeric polymers differentially cleaved by GlpQ, revealing stereochemical differences in their glycerol phosphate moieties.

Identification of the main glutamine and glutamate transporters in Staphylococcus aureus and their impact on c-di-AMP production

This study identifies glutamine and glutamate transporters in S. aureus and shows their impact on c-di-AMP production and growth in rich medium.

High-throughput transposon sequencing highlights the cell wall as an important barrier for osmotic stress in methicillin resistant Staphylococcus aureus and underlines a tailored response to different osmotic stressors

This study uses TN-seq to analyze osmotic stress responses in S. aureus, identifying gene 957 as essential under salt stress and highlighting the role of cell wall crosslinking in osmotic resistance.

GtcA is required for LTA glycosylation in Listeria monocytogenes serovar 1/2a and Bacillus subtilis

This paper shows that GtcA is essential for LTA glycosylation in L. monocytogenes and B. subtilis and suggests it functions as a C55-P-sugar flippase.

Cell shape and antibiotic resistance is maintained by the activity of multiple FtsW and RodA enzymes in Listeria monocytogenes

This study identifies multiple FtsW and RodA enzymes in Listeria monocytogenes that maintain cell shape and antibiotic resistance, with their expression regulated in response to beta-lactam antibiotics.

Inactivation of the monofunctional peptidoglycan glycosyltransferase SgtB allows Staphylococcus aureus to survive in the absence of lipoteichoic acid

This study identifies SgtB inactivation as a compensatory mechanism allowing Staphylococcus aureus to survive without lipoteichoic acid by altering peptidoglycan structure.

Cyclic-di-adenosine monophosphate (c-di-AMP) is required for osmotic regulation in Staphylococcus aureus but dispensable for viability in anaerobic conditions

This study identifies c-di-AMP's role in osmotic regulation in S. aureus but shows it is not required for anaerobic growth.