Author

J. Fadul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:zebrafish· 2 Research Focus:development & morphogenesis· 1 Assay:imaging· 1

Frequent Co-Authors

J. Rosenblatt· 2 shared D. Hedeen· 1 shared G. M. Slattum· 1 shared J. Huisken· 1 shared M. Ahmed· 1 shared M. Redd· 1 shared N. M. Redd· 1 shared S. Daetwyler· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

J. Rosenblatt

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2 papers

Recent·Most cited

Physical confinement promotes mesenchymal trans-differentiation of invading transformed cells in vivo

T. Z. Coarasa, J. Fadul, M. Ahmed, J. Rosenblatt

The paper shows that mechanical confinement drives mesenchymal trans-differentiation of invasive KRasV12-transformed cells in zebrafish, contributing to metastasis.

bioRxiv · Jul 21, 2022Cancer Biology

Basal extrusion drives cell invasion and mechanical stripping of E-cadherin

J. Fadul, G. M. Slattum, N. M. Redd, T. F. Zulueta-Coarasa, M. Redd, S. Daetwyler, D. Hedeen, J. Huisken, J. Rosenblatt

This study shows that basal extrusion drives tumor cell invasion and mechanical shedding of E-cadherin in zebrafish epidermis, with KRas mutations increasing invasion rates and p53 mutations enabling survival at distant sites.

bioRxiv · Nov 6, 2018 · PreprintCancer Biology