J. Findlay

Limited Phylogenetic Overlap Between Fluoroquinolone-Resistant Escherichia coli Isolated on Dairy Farms and those Causing Bacteriuria in Humans Living in the Same Geographical Region

The paper investigates the link between fluoroquinolone-resistant E. coli on dairy farms and human bacteriuria in the same region, finding limited phylogenetic overlap and identifying farm use patterns as risk factors.

Evidence that faecal carriage of resistant Escherichia coli by 16-week-old dogs in the United Kingdom is associated with raw feeding

This study links raw feeding in 16-week-old UK dogs to carriage of antibiotic-resistant E. coli, with some strains shared with human infections.

Reduced antibacterial drug resistance and blaCTX-M β-lactamase gene carriage in cattle-associated Escherichia coli at low temperatures, at sites dominated by older animals and on pastureland: implications for surveillance.

This study identifies factors influencing antibacterial resistance in E. coli on dairy farms, showing that lower temperatures, older animal environments, and pastureland reduce resistance and blaCTX-M gene carriage.

Molecular epidemiology of Escherichia coli producing CTX-M and plasmid AmpC-type β-lactamases from dairy farms identifies a dominant plasmid encoding CTX-M-32 but no evidence for transmission to humans in the same geographical region

The paper analyzes 3GC-R E. coli from dairy farms and human urinary samples in the same region, finding a dominant plasmid but no evidence of human transmission.

Variability in carbapenemase activity of intrinsic OxaAb (OXA-51-like) beta-lactamase enzymes in Acinetobacter baumannii

This study measures carbapenem susceptibility variability in OxaAb variants of Acinetobacter baumannii using WGS and LC-MS/MS, finding that ISAba1 promoter-driven overexpression of specific substitutions confers resistance.

Characterisation of AmpC Hyper-Producing Escherichia coli from Humans and Dairy Farms Collected in Parallel in the Same Geographical Region

This study characterizes AmpC hyper-producing E. coli from dairy farms and humans, identifies risk factors, and finds no evidence of zoonotic transmission.

Characterisation of cefotaxime-resistant urinary Escherichia coli from primary care in South-West England 2017-2018.

This study characterizes cefotaxime-resistant urinary E. coli from primary care in South-West England, finding blaCTX-M carriage as the most common resistance mechanism.

Prediction of fluoroquinolone susceptibility directly from whole genome sequence data using liquid chromatography-tandem mass spectrometry to identify mutant genotypes.

The paper predicts fluoroquinolone susceptibility in K. pneumoniae using whole genome sequence data and protein abundance measurements from liquid chromatography-tandem mass spectrometry.

The Envelope Proteome Changes Driven By RamA Overproduction in Klebsiella pneumoniae That Enhance Acquired β-Lactam Resistance

This study shows RamA overproduction in K. pneumoniae enhances β-lactam resistance by increasing efflux pumps and reducing OmpK35 porin, without altering β-lactamase levels.