Cyclosporine A Directly Affects Human and Mouse B cell Migration in vitro by Disrupting a HIF-1α Dependent, O2 Sensing, Molecular Switch
S. P. Hilchey, M. G. Palshikar, D. Li, J. Garigen, V. Cipolla, J. Thakar, M. S. Zand
This study shows cyclosporine A disrupts a HIF-1α-dependent oxygen sensing switch in B cells, affecting their migration in vitro.
bioRxiv · Apr 30, 2019 · PreprintImmunology