Generation and functional analysis of defective viral genomes during SARS-CoV-2 infection
T. Zhou, N. J. Gilliam, S. Li, S. Spaudau, R. Osborn, C. S. Anderson, T. J. Mariani, J. Thakar, S. Dewhurst, D. H. Mathews, L. Huang, Y. Sun
This study identifies DVG generation in SARS-CoV-2 and links it to IFN stimulation and persistent infection, showing higher DVG levels in symptomatic patients.
bioRxiv · Sep 22, 2022Microbiology