Author

J. H. Dyson

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

B. Tait· 1 shared C. Dickey· 1 shared D. Culbertson· 1 shared D. M. Hutt· 1 shared J. C. Sivils· 1 shared J. E. Gestwicki· 1 shared J. K. Singh· 1 shared M. B. Cox· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

B. Tait

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1 paper

Recent·Most cited

BiochemistrybioRxivSep 11, 2018

Management of Hsp90-Dependent Protein Folding by Small Molecule Targeting the Aha1 Co-Chaperone

J. K. Singh, B. Tait, N. Guy…·W. E. Balch

This study identifies SEW04784, a small molecule that disrupts Aha1-stimulated Hsp90 ATPase activity, showing therapeutic potential in prostate cancer and tauopathies without affecting basal Hsp90 function.

DOI 10.1016/j.chembiol.2020.01.008

humanexperimental assay

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