MicrobiologybioRxiv
Beyond self-resistance: ABCF ATPase LmrC is a signal-transducing component of an antibiotic-driven signaling cascade hastening the onset of lincomycin biosynthesis
M. Koberska, L. Vesela, V. Vimberg…·G. Balikova Novotna
The paper identifies LmrC, an ABCF ATPase, as a signal-transducing component that accelerates lincomycin biosynthesis in response to ribosome-targeting antibiotics through a ribosome-mediated signaling cascade.
DOI 10.1128/mbio.01731-21