Author

J. L. Coloff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

K. O. Conger· 3 shared G. M. DeNicola· 2 shared M. E. Ozgurses· 2 shared P. A. Burns· 2 shared V. Rawat· 2 shared A. Novikova· 1 shared A. Tebeje· 1 shared B.-H. Choi· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCancer Biology

K. O. Conger

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ASCT2 is the primary serine transporter in cancer cells

K. O. Conger, C. Chidley, M. E. Ozgurses, H. Zhao, Y. Kim, S. E. Semina, P. A. Burns, V. Rawat, R. Sheldon, I. Ben-Sahra, J. Frasor, P. K. Sorger, G. M. DeNicola, J. L. Coloff

This study identifies ASCT2 as the primary serine transporter in cancer cells and shows its role in purine biosynthesis and therapeutic targeting.

bioRxiv · Oct 9, 2023 · PreprintCancer Biology

Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy

V. Rawat, P. DeLear, P. Prashanth, M. E. Ozgurses, A. Tebeje, P. A. Burns, K. O. Conger, C. Solis, Y. Hasnain, A. Novikova, J. E. Endress, P. Gonzalez-Sanchez, W. Dong, G. Stephanopoulos, G. M. DeNicola, , J. L. Coloff

The paper screens drugs in human physiologic medium and identifies uric acid as an inhibitor of rigosertib's efficacy.

bioRxiv · Jul 26, 2023Cancer Biology

Lineage-Specific Silencing of PSAT1 Induces Serine Auxotrophy and Sensitivity to Dietary Serine Starvation in Luminal Breast Tumors

B.-H. Choi, K. O. Conger, L. M. Selfors, J. L. Coloff

Cell Reports · Jan 1, 2022Peer-reviewedCancer Biology