An anti-amyloidogenic treatment to specifically block the consolidation of traumatic events in mouse
P. Lopez-Garcia, D. Ramirez de Mingo, K. R. McGreevy, A. Palle Lopez, H. A. Popiel, A. Santi, Y. Nagai, J. L. Trejo, M. Carrion-Vazquez
This paper develops a transgenic mouse expressing QBP1 to block traumatic memory consolidation, showing impaired aversive memory and reduced amyloid oligomerization.
bioRxiv · Jan 21, 2020 · PreprintAnimal Behavior & Cognition