Author

J. Lachat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

P. Mergaert· 3 shared A. Yokota· 2 shared D. Naquin· 2 shared G. Lextrait· 2 shared R. Cossard· 2 shared R. Jouan· 2 shared T. Ohbayashi· 2 shared Y. Kikuchi· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMicrobiology

P. Mergaert

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Author profile →

4 papers

Recent·Most cited

Hundreds of antimicrobial peptides create a selective barrier for insect gut symbionts

J. Lachat, G. Lextrait, R. Jouan, A. Boukherissa, A. Yokota, S. Jang, K. Ishigami, R. Futahashi, R. Cossard, D. Naquin, V. Costache, L. Augusto, P. Tissiere, E. G. Biondi, B. Alunni, , P. Mergaert

The paper identifies hundreds of antimicrobial peptides in the insect gut that create a selective barrier for symbionts, with resistance mechanisms crucial for colonization.

bioRxiv · Oct 16, 2023Microbiology

Transposon sequencing reveals the essential gene set and genes enabling gut symbiosis in the insect symbiont Caballeronia insecticola

R. Jouan, G. Lextrait, J. Lachat, A. Yokota, R. Cossard, D. Naquin, T. Timtchenko, Y. Kikuchi, T. Ohbayashi, P. Mergaert

This study uses transposon sequencing to identify essential genes and gut-specific nutrients in the insect symbiont Caballeronia insecticola.

bioRxiv · Sep 7, 2023 · PreprintMicrobiology

Differential genetic strategies of Burkholderia vietnamiensis and Paraburkholderia kururiensis for root colonization of Oryza sativa ssp. japonica and ssp. indica, as revealed by Tn-seq

A. Wallner, N. Busset, J. Lachat, L. Guigard, E. King, I. Rimbault, P. Mergaert, G. Bena, L. Moulin

This study compares the genetic strategies of Burkholderia vietnamiensis and Paraburkholderia kururiensis for colonizing two rice subspecies using Tn-seq, revealing differences in fitness genes and host-specific adaptations.

bioRxiv · Apr 14, 2022 · PreprintMicrobiology

Trans-cellular tunnels induced by the fungal pathogen Candida albicans facilitate invasion through successive epithelial cells without host damage

J. Lachat, A. Pascault, D. Thibaut, R. Le Borgne, J.-M. Verbavatz, A. Weiner

This study shows Candida albicans invades epithelial cells through trans-cellular tunnels, either causing or avoiding host damage, using live-cell imaging and electron microscopy.

bioRxiv · Sep 9, 2021Microbiology